Effect of Home-based Telerehabilitation on Balance, Functional Mobility, and Quality of Life in Persons with Parkinson’s Disease: A Systematic Review and Meta-Analysis
DOI:
https://doi.org/10.63144/ijt.2025.6725Keywords:
Continuity of care, Digital health, Remote monitoring, Resource limited settings, TelerehabilitationAbstract
Background: Persons with Parkinson’s disease (PwPD) require ongoing rehabilitation to maintain independence, but traditional center-based and unsupervised home programs have limitations in accessibility and adherence. Home-based telerehabilitation (TR) offers a promising alternative by enabling remote delivery of exercise interventions. Objective: To evaluate the effect of home-based TR on balance, functional mobility, and quality of life in PwPD. Methods: A comprehensive electronic search was conducted across PubMed, CINAHL, Embase, OvidSP, ProQuest, Scopus, Web of Science, Cochrane CENTRAL, and PEDro databases. Interventional studies on exercise-centric home-based TR for PwPD with either balance, functional mobility, or quality of life as outcomes were included. Results: A total of 37 studies were included in this systematic review, of which 13 were eligible for meta-analysis. The meta-analysis revealed small but significant improvements in balance (SMD = 0.25; 95% CI: 0.04 to 0.45; p = 0.02). and functional mobility (SMD = -0.28; 95% CI: -0.52 to -0.05; p = 0.02). However, no significant effect was observed for quality of life (SMD = -0.08; 95% CI: -0.25 to 0.09; p = 0.35). Conclusion: Home-based TR is effective for improving balance and functional mobility in PwPD, although, its effect on quality of life is unclear which warrants further research.
References
Aamodt, W. W., Dahodwala, N., Bilker, W. B., Farrar, J. T., & Willis, A. W. (2023). Unique characteristics of end-of-life hospitalizations in Parkinson disease. Frontiers in Aging Neuroscience, Volume 15-2023. https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2023.1254969
Afshari, M., Hernandez, A. V, Joyce, J. M., Hauptschein, A. W., Trenkle, K. L., Stebbins, G. T., & Goetz, C. G. (2024). A novel home-based telerehabilitation program targeting fall prevention in Parkinson Disease. Neurology Clinical Practice, 14(1)., e200246. https://doi.org/10.1212/CPJ.0000000000200246
Ahn, J. H., Shin, D., Lee, D., Kim, H. Y., Youn, J., & Cho, J. W. (2024). Increasing exercise with a mobile app in people with Parkinson’s disease: A pilot study. Brain Impairment, 25(2). https://doi.org/10.1071/IB23061
An, J., Kim, J., Lai, E. C., & Lee, B.-C. (2020). Effects of a smartphone-based wearable telerehabilitation system for in-home dynamic weight-shifting balance exercises by individuals with Parkinson’s Disease. 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)., 5678–5681. https://doi.org/10.1109/EMBC44109.2020.9175967
Atterbury, E. M., & Welman, K. E. (2017). Balance training in individuals with Parkinson’s disease: Therapist-supervised vs. home-based exercise programme. Gait & Posture, 55, 138–144. https://doi.org/https://doi.org/10.1016/j.gaitpost.2017.04.006
Barker, T. H., Habibi, N., Aromataris, E., Stone, J. C., Leonardi-Bee, J., Sears, K., Hasanoff, S., Klugar, M., Tufanaru, C., Moola, S., & Munn, Z. (2024). The revised JBI critical appraisal tool for the assessment of risk of bias for quasi-experimental studies. JBI Evidence Synthesis, 22(3). https://journals.lww.com/jbisrir/fulltext/2024/03000/the_revised_jbi_critical_appraisal_tool_for_the.4.aspx
Bhalsing, K. S., Abbas, M. M., & Tan, L. C. S. (2018). Role of physical activity in Parkinson’s Disease. Annals of Indian Academy of Neurology, 21(4). https://journals.lww.com/annalsofian/fulltext/2018/21040/role_of_physical_activity_in_parkinson_s_disease.3.aspx
Bianchini, E., Onelli, C., Morabito, C., Alborghetti, M., Rinaldi, D., Anibaldi, P., Marcolongo, A., Salvetti, M., & Pontieri, F. E. (2022). Feasibility, safety, and effectiveness of telerehabilitation in mild-to-moderate Parkinson’s Disease. Frontiers in Neurology, Volume 13-2022. https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.909197
Brennan, D. M., Mawson, S., & Brownsell, S. (2009). Telerehabilitation: Enabling the remote delivery of healthcare, rehabilitation, and self management. In Advanced Technologies in Rehabilitation (pp. 231–248). IOS Press.
Carvalho, L. P., Décary, S., Beaulieu-Boire, I., Dostie, R., Lalonde, I., Texier, É., Laprise, L., Pepin, E., Gilbert, M., Corriveau, H., & Tousignant, M. (2021). Baduanjin Qigong intervention by telerehabilitation (TeleParkinson): A proof-of-concept study in Parkinson’s Disease. International Journal of Environmental Research and Public Health, 18(13). https://doi.org/10.3390/ijerph18136990
Chatto, C. A., York, P. T., Slade, C. P., & Hasson, S. M. (2018). Use of a telehealth system to enhance a home exercise program for a person with Parkinson Disease: A case report. Journal of Neurologic Physical Therapy, 42(1). https://journals.lww.com/jnpt/fulltext/2018/01000/use_of_a_telehealth_system_to_enhance_a_home.4.aspx
Chen, K., Tan, Y., Lu, Y., Wu, J., Liu, X., & Zhao, Y. (2020). Effect of exercise on quality of life in Parkinson’s Disease: A systematic review and meta-analysis. Parkinson’s Disease, 2020(1)., 3257623. https://doi.org/https://doi.org/10.1155/2020/3257623
Chen, R. (2012). Paradoxical worsening of gait with levodopa in Parkinson disease. Neurology, 78(7)., 446–447. https://doi.org/10.1212/WNL.0b013e318246d6fa
Chuang, C.-S., Chen, Y.-W., Zeng, B.-Y., Hung, C.-M., Tu, Y.-K., Tai, Y.-C., Wu, Y.-C., Hsu, C.-W., Lei, W.-T., Wu, S.-L., Stubbs, B., Carvalho, A. F., Su, K.-P., Chen, T.-Y., Tseng, P.-T., Wu, M.-K., & Tsai, C.-H. (2022). Effects of modern technology (exergame and virtual reality). assisted rehabilitation vs conventional rehabilitation in patients with Parkinson’s disease: a network meta-analysis of randomised controlled trials. Physiotherapy, 117, 35–42. https://doi.org/https://doi.org/10.1016/j.physio.2022.07.001
Cooley Hidecker, M. J., Landers, M. R., Piccorelli, A., Bush, E., & Singh, R. (2022). Coordinated speech therapy, physiotherapy, and pharmaceutical care telehealth for people with Parkinson disease in rural communities: An exploratory, 8-week cohort study for feasibility, safety, and signal of efficacy. Rural and Remote Health, 22(1)., 6679. https://doi.org/10.22605/RRH6679
Cornejo Thumm, P., Giladi, N., Hausdorff, J. M., & Mirelman, A. (2021). Tele-rehabilitation with virtual reality: A case report on the simultaneous, remote training of two patients with Parkinson Disease. American Journal of Physical Medicine & Rehabilitation, 100(5). https://journals.lww.com/ajpmr/fulltext/2021/05000/tele_rehabilitation_with_virtual_reality__a_case.5.aspx
Dhamija, R. K., Saluja, A., Garg, D., Chauhan, S., Majumdar, R., Bhardwaj, S. B., Preenja, R., Kashyap, D., & Owolabi, M. O. (2025). Teleneurorehabilitation and motor and nonmotor symptoms and quality of life in Parkinson Disease: The TELEPARK Randomized Clinical Trial. JAMA Neurology, 82(4)., 376–383. https://doi.org/10.1001/jamaneurol.2024.5387
Ellis, T. D., Cavanaugh, J. T., DeAngelis, T., Hendron, K., Thomas, C. A., Saint-Hilaire, M., Pencina, K., & Latham, N. K. (2019). Comparative effectiveness of mhealth-supported exercise compared with exercise alone for people with Parkinson Disease: Randomized Controlled Pilot Study. Physical Therapy, 99(2)., 203–216. https://doi.org/10.1093/ptj/pzy131
Ellis, T. D., Colón-Semenza, C., Deangelis, T. R., Thomas, C. A., Saint Hilaire, M. H., Earhart, G. M., & Dibble, L. E. (2021). Evidence for early and regular physical therapy and exercise in Parkinson’s Disease. Seminars in Neurology, 41(2)., 189–205. https://doi.org/10.1055/s-0041-1725133
Ellis, T., Boudreau, J. K., DeAngelis, T. R., Brown, L. E., Cavanaugh, J. T., Earhart, G. M., Ford, M. P., Foreman, K. B., & Dibble, L. E. (2013). Barriers to exercise in people with Parkinson Disease. Physical Therapy, 93(5)., 628–636. https://doi.org/10.2522/ptj.20120279
Ernst, M., Folkerts, A. K., Gollan, R., Lieker, E., Caro-Valenzuela, J., Adams, A., Cryns, N., Monsef, I., Dresen, A., Roheger, M., Eggers, C., Skoetz, N., & Kalbe, E. (2023). Physical exercise for people with Parkinson's disease: A systematic review and network meta-analysis. The Cochrane database of systematic reviews, 1(1), CD013856. https://doi.org/10.1002/14651858.CD013856.pub2
Factor, S. A., Steenland, N. K., Higgins, D. S., Molho, E. S., Kay, D. M., Montimurro, J., Rosen, A. R., Zabetian, C. P., & Payami, H. (2011). Postural instability/gait disturbance in Parkinson’s disease has distinct subtypes: An exploratory analysis. Journal of Neurology, Neurosurgery & Psychiatry, 82(5)., 564. https://doi.org/10.1136/jnnp.2010.222042
Ferrari, A. J., Santomauro, D. F., Aali, A., Abate, Y. H., Abbafati, C., Abbastabar, H., Abd ElHafeez, S., Abdelmasseh, M., Abd-Elsalam, S., Abdollahi, A., Abdullahi, A., Abegaz, K. H., Abeldaño Zuñiga, R. A., Aboagye, R. G., Abolhassani, H., Abreu, L. G., Abualruz, H., Abu-Gharbieh, E., Abu-Rmeileh, N. M. E., … Murray, C. J. L. (2024). Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet, 403(10440)., 2133–2161. https://doi.org/10.1016/S0140-6736(24)00757-8
Fırat, E. Y., Turgay, T., Soğan, S. S., & Günel Karadeniz, P. (2023). Effects of LSVT-BIG via telerehabilitation on non-motor and motor symptoms and quality of life in Parkinson’s disease. Acta Neurologica Belgica, 123(1)., 207–214. https://doi.org/10.1007/s13760-022-02104-x
Flynn, A., Preston, E., Dennis, S., Canning, C. G., & Allen, N. E. (2020). Home-based exercise monitored with telehealth is feasible and acceptable compared to centre-based exercise in Parkinson’s disease: A randomised pilot study. Clinical Rehabilitation, 35(5)., 728–739. https://doi.org/10.1177/0269215520976265
Flynn, A., Allen, N. E., Dennis, S., Canning, C. G., & Preston, E. (2019). Home-based prescribed exercise improves balance-related activities in people with Parkinson’s disease and has benefits similar to centre-based exercise: a systematic review. Journal of Physiotherapy, 65(4)., 189–199. https://doi.org/https://doi.org/10.1016/j.jphys.2019.08.003
Gandolfi, M., Geroin, C., Dimitrova, E., Boldrini, P., Waldner, A., Bonadiman, S., Picelli, A., Regazzo, S., Stirbu, E., Primon, D., Bosello, C., Gravina, A. R., Peron, L., Trevisan, M., Garcia, A. C., Menel, A., Bloccari, L., Valè, N., Saltuari, L., … Smania, N. (2017). Virtual reality telerehabilitation for postural instability in Parkinson’s Disease: A multicenter, single-blind, randomized, controlled trial. BioMed Research International, 2017(1)., 7962826. https://doi.org/https://doi.org/10.1155/2017/7962826
Ge, Y., Zhao, W., Zhang, L., Zhao, X., Shu, X., Li, J., Qiao, L., Liu, Y., & Wang, H. (2024). Home physical therapy versus telerehabilitation in improving motor function and quality of life in Parkinson’s disease: A randomized controlled trial. BMC Geriatrics, 24(1)., 968. https://doi.org/10.1186/s12877-024-05529-6
Ginis, P., Nieuwboer, A., Dorfman, M., Ferrari, A., Gazit, E., Canning, C. G., Rocchi, L., Chiari, L., Hausdorff, J. M., & Mirelman, A. (2016). Feasibility and effects of home-based smartphone-delivered automated feedback training for gait in people with Parkinson’s disease: A pilot randomized controlled trial. Parkinsonism & Related Disorders, 22, 28–34. https://doi.org/10.1016/j.parkreldis.2015.11.004
Goffredo, M., Baglio, F., De Icco, R., Proietti, S., Maggioni, G., Turolla, A., Pournajaf, S., Jonsdottir, J., Zeni, F., Federico, S., Cacciante, L., Cioeta, M., Tassorelli, C., Franceschini, M., & Calabrò, R. S. (2023). Efficacy of non-immersive virtual reality-based telerehabilitation on postural stability in Parkinson’s disease: A multicenter randomized controlled trial. European Journal of Physical and Rehabilitation Medicine, 59(6)., 689–696. https://doi.org/10.23736/S1973-9087.23.07954-6
Gondim, I. T. G. de O., Lins, C. C. dos S. A., Asano, N. M. J., Asano, A. G. C., Cabral, E. D., & Coriolano, M. das G. W. de S. (2017). Individualized guidance and telephone monitoring in a self-supervised home-based physiotherapeutic program in Parkinson. Fisioterapia Em Movimento, 30(3)., 559–568.
Gopal, A., Bonanno, V., Block, V. J., & Bove, R. M. (2022). Accessibility to telerehabilitation services for people with multiple sclerosis: Analysis of barriers and limitations. International Journal of MS Care, 24(6)., 260–265.
Grigorovich, A., Xi, M., Lam, N., Pakosh, M., & Chan, B. C. F. (2022). A systematic review of economic analyses of home-based telerehabilitation. Disability and Rehabilitation, 44(26)., 8188–8200. https://doi.org/10.1080/09638288.2021.2019327
Gutierrez-Arias, R., Gonzalez-Mondaca, C., Marinkovic-Riffo, V., Ortiz-Puebla, M., Paillan-Reyes, F., & Seron, P. (2025). Measures to ensure safety during telerehabilitation of people with stroke: A scoping review. Journal of Telemedicine and Telecare, 31(2)., 198–206.
Hardeman, L. E. S., Geerse, D. J., Hoogendoorn, E. M., Nonnekes, J., & Roerdink, M. (2024). Remotely prescribed and monitored home-based gait-and-balance therapeutic exergaming using augmented reality (AR). glasses: Protocol for a clinical feasibility study in people with Parkinson’s disease. Pilot and Feasibility Studies, 10(1)., 54. https://doi.org/10.1186/s40814-024-01480-w
Holmes, J. D., Gu, M. L., Johnson, A. M., & Jenkins, M. E. (2013). The effects of a home-based virtual reality rehabilitation program on balance among individuals with Parkinson’s Disease. Physical & Occupational Therapy In Geriatrics, 31(3)., 241–253. https://doi.org/10.3109/02703181.2013.814743
Horin, A. P., McNeely, M. E., Harrison, E. C., Myers, P. S., Sutter, E. N., Rawson, K. S., & Earhart, G. M. (2019). Usability of a daily mhealth application designed to address mobility, speech and dexterity in Parkinson’s Disease. Neurodegenerative Disease Management, 9(2)., 97–105. https://doi.org/10.2217/nmt-2018-0036
Isernia, S., Di Tella, S., Pagliari, C., Jonsdottir, J., Castiglioni, C., Gindri, P., Salza, M., Gramigna, C., Palumbo, G., Molteni, F., & Baglio, F. (2020). Effects of an innovative telerehabilitation intervention for people with Parkinson’s Disease on quality of life, motor, and non-motor abilities. Frontiers in Neurology, Volume 11-2020. https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.00846
Jankovic, J., McDermott, M., Carter, J., Gauthier, S., Goetz, C., Golbe, L., Huber, S., Koller, W., Olanow, C., Shoulson, I., Stern, M., Tanner, C., Weiner, W., & Group, P. S. (1990). Variable expression of Parkinson’s disease. Neurology, 40(10)., 1529. https://doi.org/10.1212/WNL.40.10.1529
Johnson, J. K., Longhurst, J. K., Gevertzman, M., Jefferson, C., Linder, S. M., Bethoux, F., & Stilphen, M. (2024). The Use of telerehabilitation to improve movement-related outcomes and quality of life for individuals with Parkinson Disease: Pilot randomized controlled trial. JMIR Form Res, 8, e54599. https://doi.org/10.2196/54599
Khalil, H., Busse, M., Quinn, L., Nazzal, M., Batyha, W., Alkhazaleh, S., & Alomari, M. A. (2017). A pilot study of a minimally supervised home exercise and walking program for people with Parkinson’s Disease in Jordan. Neurodegenerative Disease Management, 7(1)., 73–84. https://doi.org/10.2217/nmt-2016-0041
Kim, M., Kim, E., Kim, M., Moon, S. M., Kim, M., Kim, D., Je, S. H., & Kang, H. (2025). Motivators and barriers affecting exercise in patients with Parkinson’s Disease. Journal of Clinical Neurology, 21(1)., 13–20. https://doi.org/10.3988/jcn.2024.0328
Kwok, J. Y. Y., Lee, J. J., Choi, E. P. H., Chau, P. H., & Auyeung, M. (2022). Stay mindfully active during the coronavirus pandemic: a feasibility study of mHealth-delivered mindfulness yoga program for people with Parkinson’s disease. BMC Complementary Medicine and Therapies, 22(1), 37. https://doi.org/10.1186/s12906-022-03519-y
Kwon, S.-H., Park, J. K., & Koh, Y. H. (2023). A systematic review and meta-analysis on the effect of virtual reality-based rehabilitation for people with Parkinson’s disease. Journal of NeuroEngineering and Rehabilitation, 20(1)., 94. https://doi.org/10.1186/s12984-023-01219-3
Lacroix, A., Kressig, R. W., Muehlbauer, T., Gschwind, Y. J., Pfenninger, B., Bruegger, O., & Granacher, U. (2015). Effects of a supervised versus an unsupervised combined balance and strength training program on balance and muscle power in healthy older adults: A randomized controlled trial. Gerontology, 62(3)., 275–288. https://doi.org/10.1159/000442087
Lai, B., Bond, K., Kim, Y., Barstow, B., Jovanov, E., & Bickel, C. S. (2018). Exploring the uptake and implementation of tele-monitored home-exercise programmes in adults with Parkinson’s disease: A mixed-methods pilot study. Journal of Telemedicine and Telecare, 26(1–2)., 53–63. https://doi.org/10.1177/1357633X18794315
Landers, M. R., & Ellis, T. D. (2020). A mobile app specifically designed to facilitate exercise in Parkinson Disease: Single-cohort pilot study on feasibility, safety, and signal of efficacy. JMIR Mhealth Uhealth, 8(10)., e18985. https://doi.org/10.2196/18985
Langer, A., Gassner, L., Flotz, A., Hasenauer, S., Gruber, J., Wizany, L., Pokan, R., Maetzler, W., & Zach, H. (2021). How COVID-19 will boost remote exercise-based treatment in Parkinson’s disease: A narrative review. Npj Parkinson’s Disease, 7(1)., 25. https://doi.org/10.1038/s41531-021-00160-3
Lavoie, V., Bouchard, M., Turcotte, S., & Tousignant, M. (2021). Telerehabilitation for individuals with Parkinson’s disease and a history of falls: A pilot study. Physiotherapy Canada, 73(4)., 343–350.
McGuinness, L. A., & Higgins, J. P. T. (2021). Risk-of-bias VISualization (robvis).: An R package and Shiny web app for visualizing risk-of-bias assessments. Research Synthesis Methods, 12(1)., 55–61. https://doi.org/https://doi.org/10.1002/jrsm.1411
Munn, Z., Barker, T. H., Moola, S., Tufanaru, C., Stern, C., McArthur, A., Stephenson, M., & Aromataris, E. (2020). Methodological quality of case series studies: An introduction to the JBI critical appraisal tool. JBI Evidence Synthesis, 18(10). https://journals.lww.com/jbisrir/fulltext/2020/10000/methodological_quality_of_case_series_studies__an.5.aspx
Okusa, S., Saegusa, H., Miyakawa, K., Tsutsumi, Y., Ishida, S., Nishikata, K., Nukariya, T., Tezuka, T., Nihei, Y., Kitagawa, Y., Kubo, S., Suzuki, N., Nakahara, J., & Seki, M. (2025). Satisfaction, effectiveness, and usability of telerehabilitation for Parkinson’s disease patients. Journal of Rehabilitation Medicine, 57. https://doi.org/10.2340/jrm.v57.39819
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71
Park, C., & Lee, B.-C. (2024). A systematic review of the effects of interactive telerehabilitation with remote monitoring and guidance on balance and gait performance in older adults and individuals with neurological conditions. Bioengineering, 11(5). https://doi.org/10.3390/bioengineering11050460
Pastana Ramos, L. F., Vilacorta-Pereira, T. de C. S., Duarte, J. dos S., Yamada, E. S., & Santos-Lobato, B. L. (2023). Feasibility and effectiveness of a remote individual rehabilitation program for people with Parkinson’s disease living in the Brazilian Amazon: A randomized clinical trial. Frontiers in Neurology, Volume 14-2023.
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1244661
Pourahmad, R., Saleki, K., Esmaili, M., Abdollahi, A., Alijanizadeh, P., Gholinejad, M. Z., Banazadeh, M., & Ahmadi, M. (2023). Deep brain stimulation (DBS) as a therapeutic approach in gait disorders: What does it bring to the table? IBRO Neuroscience Reports, 14, 507–513. https://doi.org/10.1016/j.ibneur.2023.05.008
Pramuka, M., & van Roosmalen, L. (2009). Telerehabilitation technologies: Accessibility and usability. International Journal of Telerehabilitation, 1(1)., 85–98. https://doi.org/10.5195/ijt.2009.6016
Putzolu, M., Manzini, V., Gambaro, M., Cosentino, C., Bonassi, G., Botta, A., Ravizzotti, E., Avanzino, L., Pelosin, E., & Mezzarobba, S. (2023). Home-based exercise training by using a smartphone app in patients with Parkinson’s disease: A feasibility study. Frontiers in Neurology, Volume 14-2023. https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1205386
Schootemeijer, S., van der Kolk, N. M, Ellis, T., Mirelman, A., Nieuwboer, A., Nieuwhof, F., Schwarzschild, M. A., de Vries, N. M., & Bloem, B. R. (2020a). Barriers and motivators to engage in exercise for persons with Parkinson’s Disease. Journal of Parkinson’s Disease, 10(4)., 1293–1299. https://doi.org/10.3233/JPD-202247
Schootemeijer, S., van der Kolk, N. M., Bloem, B. R., & de Vries, N. M. (2020b). Current perspectives on aerobic exercise in people with Parkinson’s Disease. Neurotherapeutics, 17(4)., 1418–1433. https://doi.org/10.1007/s13311-020-00904-8
Silva-Batista, C., de Almeida, F. O., Wilhelm, J. L., Horak, F. B., Mancini, M., & King, L. A. (2024). Telerehabilitation by videoconferencing for balance and gait in people with Parkinson’s Disease: A scoping review. Geriatrics, 9(3). https://doi.org/10.3390/geriatrics9030066
Smulders, K., Dale, M. L., Carlson-Kuhta, P., Nutt, J. G., & Horak, F. B. (2016). Pharmacological treatment in Parkinson’s disease: Effects on gait. Parkinsonism & Related Disorders, 31, 3–13. https://doi.org/https://doi.org/10.1016/j.parkreldis.2016.07.006
Sterne, J. A. C., Savović, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., Cates, C. J., Cheng, H.-Y., Corbett, M. S., Eldridge, S. M., Emberson, J. R., Hernán, M. A., Hopewell, S., Hróbjartsson, A., Junqueira, D. R., Jüni, P., Kirkham, J. J., Lasserson, T., Li, T., … Higgins, J. P. T. (2019). RoB 2: A revised tool for assessing risk of bias in randomised trials. BMJ, 366, l4898. https://doi.org/10.1136/bmj.l4898
Su, D., Cui, Y., He, C., Yin, P., Bai, R., Zhu, J., Lam, J. S. T., Zhang, J., Yan, R., Zheng, X., Wu, J., Zhao, D., Wang, A., Zhou, M., & Feng, T. (2025). Projections for prevalence of Parkinson’s disease and its driving factors in 195 countries and territories to 2050: Modelling study of Global Burden of Disease Study 2021. BMJ, 388, e080952. https://doi.org/10.1136/bmj-2024-080952
Tarazi, F. I., Sahli, Z. T., Wolny, M., & Mousa, S. A. (2014). Emerging therapies for Parkinson’s disease: From bench to bedside. Pharmacology & Therapeutics, 144(2)., 123–133. https://doi.org/10.1016/J.PHARMTHERA.2014.05.010
Thenganatt, M. A., & Jankovic, J. (2014). Parkinson Disease Subtypes. JAMA Neurology, 71(4)., 499–504. https://doi.org/10.1001/jamaneurol.2013.6233
Uche-Okoye, D., Ajemba, M. N., Amy, B., Arene, E. C., Ugo, C. H., Eze, N. P., Anyadike, I. K., Onuorah, U. M., & Chiwenite, C. M. (2023). Is telerehabilitation an effective maintenance strategy for patients with chronic obstructive pulmonary diseases: A systematic review. Bulletin of the National Research Centre, 47(1)., 13. https://doi.org/10.1186/s42269-023-00980-8
van der Heeden, J. F., Marinus, J., Martinez-Martin, P., Rodriguez-Blazquez, C., Geraedts, V. J., & van Hilten, J. J. (2016). Postural instability and gait are associated with severity and prognosis of Parkinson disease. Neurology, 86(24)., 2243–2250. https://doi.org/10.1212/WNL.0000000000002768
van der Kolk, N. M., de Vries, N. M., Kessels, R. P. C., Joosten, H., Zwinderman, A. H., Post, B., & Bloem, B. R. (2019). Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson’s disease: a double-blind, randomised controlled trial. The Lancet Neurology, 18(11)., 998–1008. https://doi.org/10.1016/S1474-4422(19).30285-6
Vasconcellos, L. S. de, Silva, R. S., Pachêco, T. B. F., Nagem, D. A. P., Sousa, C. de O., & Ribeiro, T. S. (2023). Telerehabilitation-based trunk exercise training for motor symptoms of individuals with Parkinson’s disease: A randomized controlled clinical trial. Journal of Telemedicine and Telecare, 29(9)., 698–706.
Velez, M., Lugo-Agudelo, L. H., Patiño Lugo, D. F., Glenton, C., Posada, A. M., Mesa Franco, L. F., Negrini, S., Kiekens, C., Spir Brunal, M. A., Roberg, A.-Sb., & al., et. (2023). Factors that influence the provision of home‐based rehabilitation services for people needing rehabilitation: A qualitative evidence synthesis. Cochrane Database of Systematic Reviews, 2. https://doi.org/10.1002/14651858.CD014823
Vellata, C., Belli, S., Balsamo, F., Giordano, A., Colombo, R., & Maggioni, G. (2021). Effectiveness of telerehabilitation on motor impairments, non-motor symptoms and compliance in patients with Parkinson’s Disease: A Systematic Review. Frontiers in Neurology, 12. https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.627999
Vu, T. C., Nutt, J. G., & Holford, N. H. G. (2012). Progression of motor and nonmotor features of Parkinson’s disease and their response to treatment. British Journal of Clinical Pharmacology, 74(2)., 267–283. https://doi.org/https://doi.org/10.1111/j.1365-2125.2012.04192.x
Wagner, L., Hauptmann, B., Hoffmann, A.-K., Jochems, N., Schmeier, B., Schrader, A., Kohlmann, T., & Deck, R. (2022). Evaluation of an individualized, tablet-based physiotherapy training programme for patients with Parkinson’s disease: the ParkProTrain study, a quasi-randomised controlled trial. BMC Neurology, 22(1)., 176. https://doi.org/10.1186/s12883-022-02647-9
Walton, L., Domellöf, M. E., Åström, Å. N., Elowson, Å., & Neely, A. S. (2022). Digital dance for people with Parkinson’s Disease During the COVID-19 Pandemic: A feasibility study. Frontiers in Neurology, Volume 12-2021. https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.743432
Wang, Q., Chen, Y., Li, L., Li, C., Li, L., Cao, H., & Yang, H. (2023). Barriers to home exercise for patients with Parkinson’s disease: A qualitative study. BMJ Open, 13(2)., e061932. https://doi.org/10.1136/bmjopen-2022-061932
Weise, D., Claus, I., Dresel, C., Kalbe, E., Liepelt-Scarfone, I., Lorenzl, S., Redecker, C., & Urban, P. P. (2024). Multidisciplinary care in Parkinson’s disease. Journal of Neural Transmission, 131(10)., 1217–1227. https://doi.org/10.1007/s00702-024-02807-w
Yang, Y., Fu, X., Zhang, H., Ouyang, G., & Lin, S.-C. (2023). The effect of home-based exercise on motor symptoms, quality of life and functional performance in Parkinson’s disease: A systematic review and meta-analysis. BMC Geriatrics, 23(1)., 873. https://doi.org/10.1186/s12877-023-04595-6
Zhong, W., Liu, R., Cheng, H., Xu, L., Wang, L., He, C., & Wei, Q. (2023). Longer-term effects of cardiac telerehabilitation on patients with coronary artery disease: Systematic review and meta-analysis. JMIR Mhealth Uhealth, 11, e46359. https://doi.org/10.2196/46359
Zhou, X., Zhao, P., Guo, X., Wang, J., & Wang, R. (2022). Effectiveness of aerobic and resistance training on the motor symptoms in Parkinson’s disease: Systematic review and network meta-analysis. Frontiers in Aging Neuroscience, 14, 935176.
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Copyright (c) 2025 Arnold Fredrick D'Souza, Akhila Jagadish, Jennifer V. D'souza, Dorcas B. C. Gandhi, Dushyanth Babu Jasti, Manikandan Natarajan
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